1. Preparation Before Cleaning

As one of indispensable equipment for producing medicinal capsules, the automatic capsule filling machine produced by Grand machinery will also usher in great development opportunities. Integrating machine, electricity and gas, the capsule filling machine adopts microcomputer programmable controller, touch panel operation, variable frequency speed control, equipped with electronic automatic devices, can automatically complete empty capsule feeding, separation, filling, locking and other processes. As a result, it reduces human labor intensity but improves efficiency, and also meets requirements of pharmaceutical hygiene GMP. Therefore, there are strict requirements for cleaning. Now, let's take a look at the preparation of the manufacturers before cleaning the automatic capsule filling machine.

1.1. Cleaning frequency

(1) After the end of each batch of production;

(2) After each shift of continuous production;

(3) Cleaning and disinfecting before and after production;

(4) Clean when replacing varieties, specifications and batch numbers;

(5) Cleaning and sterilizing the whole machine after equipment maintenance.

      1.2. Cleaning tools

Tools: cleaning cloth, vacuum cleaner, brush, cleaning basin, etc.

Detergents and disinfectants: drinking water, purified water, 75% ethanol.

Method: according to the order of dismantling >> washing, inside >> outside, parts >> whole machine.

2. Cleaning Procedure

After making preparations, we will start to clean the machine. For different varieties, we have different cleaning steps:

Cleaning steps for producing the same batch

(1) Use a vacuum cleaner and a soft brush to clean residual powder in the module of powder filling device;

(2) Remove powder filling rod, dosing disk, and powder hopper, take them to cleaning room and rinse with drinking water then with purified water. Afterwards, dry them with a dry cleaning cloth first and then wipe with 75% ethanol;

(3) As fore the contact parts with the powder, please scrub with purified water first, then dry with a dry cloth, and next wipe and disinfect with 75% ethanol;

(4) The glass protective cover and machine surface should be scrubbed with purified water;

(5) Clean up the site. After passing the inspection, hang the "Cleaned" sign;

(6) Record the cleaning information.

Cleaning steps for replacing batch

After the cleaning steps for producing the same variety mentioned above, please complete the following steps:

(1) Unload capsule barrel and capsule funnel >> rinse with purified water in cleaning room >> dry with a dry cleaning cloth >> wipe and disinfect with 75% ethanol;

(2) Scrub cam disc movable support: with purified water >> with a dry cleaning cloth >> with 75% ethanol to disinfect.

3. Install

Please install the machine according to the video below step by step:

00:01: 1. Install intermediate ring

00:05: 2. Install metering disc washer

00:20: 3. Install copper spacing ring

00:25: 4. Install powder blocking piece

00:35: 5. Install metering panel

00:50: 6. Install powder blocking ring or metering panel

01:15: 6. Install powder blocking ring

02:05: 7. Install filling base  

02:45: 8. Install filling rod

02:55: 9. Align and fix the position of filling rod and metering panel

03:15: 9. Install the remaining 5 filling rod modules

03:30: 9. Filling rod position is defined according to the scale

03:55: 10: Install the screw rod to fix the filling rod

04:30: 11. Install the filling screw rod coat

04:50: 12. Install capsule pushing port (discharge port)

05:40: 13. Install upper and lower modules and then calibrate

06:35: 13. Install the remaining 11 sets of modules in turn

07:10: 14. Install capsule locking device

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